Hutchinson-Gilford Progeria Syndrome (HGPS), also known as progeria, is an extremely rare and fatal genetic disorder that causes accelerated aging in children, and ultimately death due to complications from severe atherosclerosis. Although only a few hundred children are affected by HGPS worldwide, there is a huge need to spread awareness of this devastating condition, and to develop innovative interventions that can halt the underlying cause of the disease to allow patients to survive and thrive into adulthood and beyond.